Type I and type II errors

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In statistical hypothesis testing, a type I error is the incorrect rejection of a true null hypothesis (also known as a "false positive" finding), while a type II error is incorrectly retaining a false null hypothesis (also known as a "false negative" finding). More simply stated, a type I error is to falsely infer the existence of something that is not there, while a type II error is to falsely infer the absence of something that is.

Video Type I and type II errors

Definition

In statistics, a null hypothesis is a statement that one seeks to nullify with evidence to the contrary. Most commonly it is a statement that the phenomenon being studied produces no effect or makes no difference. An example of a null hypothesis is the statement "This diet has no effect on people's weight." Usually, an experimenter frames a null hypothesis with the intent of rejecting it: that is, intending to run an experiment which produces data that shows that the phenomenon under study does make a difference. In some cases there is a specific alternative hypothesis that is opposed to the null hypothesis, in other cases the alternative hypothesis is not explicitly stated, or is simply "the null hypothesis is false" - in either event, this is a binary judgment, but the interpretation differs and is a matter of significant dispute in statistics.

A type I error (or error of the first kind) is the incorrect rejection of a true null hypothesis. Usually a type I error leads one to conclude that a supposed effect or relationship exists when in fact it doesn't. Examples of type I errors include a test that shows a patient to have a disease when in fact the patient does not have the disease, a fire alarm going on indicating a fire when in fact there is no fire, or an experiment indicating that a medical treatment should cure a disease when in fact it does not.

A type II error (or error of the second kind) is the failure to reject a false null hypothesis. Examples of type II errors would be a blood test failing to detect the disease it was designed to detect, in a patient who really has the disease; a fire breaking out and the fire alarm does not ring; or a clinical trial of a medical treatment failing to show that the treatment works when really it does.

In terms of false positives and false negatives, a positive result corresponds to rejecting the null hypothesis, while a negative result corresponds to failing to reject the null hypothesis; "false" means the conclusion drawn is incorrect. Thus a type I error is a false positive, and a type II error is a false negative.

When comparing two means, concluding the means were different when in reality they were not different would be a Type I error; concluding the means were not different when in reality they were different would be a Type II error. Various extensions have been suggested as "Type III errors", though none have wide use.

All statistical hypothesis tests have a probability of making type I and type II errors. For example, all blood tests for a disease will falsely detect the disease in some proportion of people who don't have it, and will fail to detect the disease in some proportion of people who do have it. A test's probability of making a type I error is denoted by ?. A test's probability of making a type II error is denoted by ?. These error rates are traded off against each other: for any given sample set, the effort to reduce one type of error generally results in increasing the other type of error. For a given test, the only way to reduce both error rates is to increase the sample size, and this may not be feasible.

These terms are also used in a more general way by social scientists and others to refer to flaws in reasoning. This article is specifically devoted to the statistical meanings of those terms and the technical issues of the statistical errors that those terms describe.

Maps Type I and type II errors

Statistical test theory

In statistical test theory, the notion of statistical error is an integral part of hypothesis testing. The test requires an unambiguous statement of a null hypothesis, which usually corresponds to a default "state of nature", for example "this person is healthy", "this accused is not guilty" or "this product is not broken". An alternative hypothesis is the negation of null hypothesis, for example, "this person is not healthy", "this accused is guilty" or "this product is broken". The result of the test may be negative, relative to the null hypothesis (not healthy, guilty, broken) or positive (healthy, not guilty, not broken). If the result of the test corresponds with reality, then a correct decision has been made. However, if the result of the test does not correspond with reality, then an error has occurred. Due to the statistical nature of a test, the result is never, except in very rare cases, free of error. Two types of error are distinguished: type I error and type II error.

Type I error

A type I error occurs when the null hypothesis (H₀) is true, but is rejected. It is asserting something that is absent, a false hit. A type I error may be likened to a so-called false positive (a result that indicates that a given condition is present when it actually is not present).

The type I error rate or significance level is the probability of rejecting the null hypothesis given that it is true. It is denoted by the Greek letter ? (alpha) and is also called the alpha level. Often, the significance level is set to 0.05 (5%), implying that it is acceptable to have a 5% probability of incorrectly rejecting the null hypothesis.

Type II error

A type II error occurs when the null hypothesis is false, but erroneously fails to be rejected. It is failing to assert what is present, a miss. A type II error may be compared with a so-called false negative (where an actual 'hit' was disregarded by the test and seen as a 'miss') in a test checking for a single condition with a definitive result of true or false. A Type II error is committed when we fail to believe a true alternative hypothesis. In terms of folk tales, an investigator may fail to see the wolf ("failing to raise an alarm"). Again, H₀: no wolf.

The rate of the type II error is denoted by the Greek letter ? (beta) and related to the power of a test (which equals 1-?).

Table of error types

Tabularised relations between truth/falseness of the null hypothesis and outcomes of the test:

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Examples

Example 1

Hypothesis: "Adding water to toothpaste protects against cavities."

Null hypothesis (H₀): "Adding water to toothpaste has no effect on cavities."

This null hypothesis is tested against experimental data with a view to nullifying it with evidence to the contrary.

A type I error occurs when detecting an effect (adding water to toothpaste protects against cavities) that is not present. The null hypothesis is true (i.e., it is true that adding water to toothpaste has no effect on cavities), but this null hypothesis is rejected based on bad experimental data.

Example 2

Hypothesis: "Adding fluoride to toothpaste protects against cavities."

Null hypothesis (H₀): "Adding fluoride to toothpaste has no effect on cavities."

This null hypothesis is tested against experimental data with a view to nullifying it with evidence to the contrary.

A type II error occurs when failing to detect an effect (adding fluoride to toothpaste protects against cavities) that is present. The null hypothesis is false (i.e., adding fluoride is actually effective against cavities), but the experimental data is such that the null hypothesis cannot be rejected.

Example 3

Hypothesis: "The evidence produced before the court proves that this man is guilty."

Null hypothesis (H₀): "This man is innocent."

A type I error occurs when convicting an innocent person (a miscarriage of justice). A type II error occurs when letting a guilty person go free (an error of impunity).

A positive correct outcome occurs when convicting a guilty person. A negative correct outcome occurs when letting an innocent person go free.

Example 4

Hypothesis: "A patient's symptoms improve after treatment A more rapidly than after a placebo treatment."

Null hypothesis (H₀): "A patient's symptoms after treatment A are indistinguishable from a placebo."

A Type I error would falsely indicate that treatment A is more effective than the placebo, whereas a Type II error would be a failure to demonstrate that treatment A is more effective than placebo even though it actually is more effective.

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Etymology

In 1928, Jerzy Neyman (1894-1981) and Egon Pearson (1895-1980), both eminent statisticians, discussed the problems associated with "deciding whether or not a particular sample may be judged as likely to have been randomly drawn from a certain population"^p. 1: and, as Florence Nightingale David remarked, "it is necessary to remember the adjective 'random' [in the term 'random sample'] should apply to the method of drawing the sample and not to the sample itself".

They identified "two sources of error", namely:

(a) the error of rejecting a hypothesis that should have been accepted, and

(b) the error of accepting a hypothesis that should have been rejected.^p.31

In 1930, they elaborated on these two sources of error, remarking that:

...in testing hypotheses two considerations must be kept in view, (1) we must be able to reduce the chance of rejecting a true hypothesis to as low a value as desired; (2) the test must be so devised that it will reject the hypothesis tested when it is likely to be false.

In 1933, they observed that these "problems are rarely presented in such a form that we can discriminate with certainty between the true and false hypothesis" (p. 187). They also noted that, in deciding whether to accept or reject a particular hypothesis amongst a "set of alternative hypotheses" (p. 201), H₁, H₂, . . ., it was easy to make an error:

...[and] these errors will be of two kinds:

(I) we reject H₀ [i.e., the hypothesis to be tested] when it is true,

(II) we accept H₀ when some alternative hypothesis H_A or H₁ is true.^p.187 (There are various notations for the alternative).

In all of the papers co-written by Neyman and Pearson the expression H₀ always signifies "the hypothesis to be tested".

In the same paper^p. 190 they call these two sources of error, errors of type I and errors of type II respectively.

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Related terms

Null hypothesis

It is standard practice for statisticians to conduct tests in order to determine whether or not a "speculative hypothesis" concerning the observed phenomena of the world (or its inhabitants) can be supported. The results of such testing determine whether a particular set of results agrees reasonably (or does not agree) with the speculated hypothesis.

On the basis that it is always assumed, by statistical convention, that the speculated hypothesis is wrong, and the so-called "null hypothesis" that the observed phenomena simply occur by chance (and that, as a consequence, the speculated agent has no effect) - the test will determine whether this hypothesis is right or wrong. This is why the hypothesis under test is often called the null hypothesis (most likely, coined by Fisher (1935, p. 19)), because it is this hypothesis that is to be either nullified or not nullified by the test. When the null hypothesis is nullified, it is possible to conclude that data support the "alternative hypothesis" (which is the original speculated one).

The consistent application by statisticians of Neyman and Pearson's convention of representing "the hypothesis to be tested" (or "the hypothesis to be nullified") with the expression H₀ has led to circumstances where many understand the term "the null hypothesis" as meaning "the nil hypothesis" - a statement that the results in question have arisen through chance. This is not necessarily the case - the key restriction, as per Fisher (1966), is that "the null hypothesis must be exact, that is free from vagueness and ambiguity, because it must supply the basis of the 'problem of distribution,' of which the test of significance is the solution." As a consequence of this, in experimental science the null hypothesis is generally a statement that a particular treatment has no effect; in observational science, it is that there is no difference between the value of a particular measured variable, and that of an experimental prediction.

Statistical significance

If the probability of obtaining a result as extreme as the one obtained, supposing that the null hypothesis were true, is lower than a pre-specified cut-off probability (for example, 5%), then the result is said to be statistically significant and the null hypothesis is rejected.

British statistician Sir Ronald Aylmer Fisher (1890-1962) stressed that the "null hypothesis":

... is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.

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Application domains

Statistical tests always involve a trade-off between:

1. the acceptable level of false positives (in which a non-match is declared to be a match) and
2. the acceptable level of false negatives (in which an actual match is not detected).

A threshold value can be varied to make the test more restrictive or more sensitive, with the more restrictive tests increasing the risk of rejecting true positives, and the more sensitive tests increasing the risk of accepting false positives.

Inventory control

An automated inventory control system that rejects high-quality goods of a consignment commits a type I error, while a system that accepts low-quality goods commits a type II error.

Computers

The notions of false positives and false negatives have a wide currency in the realm of computers and computer applications, as follows.

Computer security

Security vulnerabilities are an important consideration in the task of keeping computer data safe, while maintaining access to that data for appropriate users. Moulton (1983), stresses the importance of:

• avoiding the type I errors (or false positives) that classify authorized users as imposters.
• avoiding the type II errors (or false negatives) that classify imposters as authorized users.

Spam filtering

A false positive occurs when spam filtering or spam blocking techniques wrongly classify a legitimate email message as spam and, as a result, interferes with its delivery. While most anti-spam tactics can block or filter a high percentage of unwanted emails, doing so without creating significant false-positive results is a much more demanding task.

A false negative occurs when a spam email is not detected as spam, but is classified as non-spam. A low number of false negatives is an indicator of the efficiency of spam filtering.

Malware

The term "false positive" is also used when antivirus software wrongly classifies a harmless file as a virus. The incorrect detection may be due to heuristics or to an incorrect virus signature in a database. Similar problems can occur with antitrojan or antispyware software.

Optical character recognition

Detection algorithms of all kinds often create false positives. Optical character recognition (OCR) software may detect an "a" where there are only some dots that appear to be an "a" to the algorithm being used.

Security screening

False positives are routinely found every day in airport security screening, which are ultimately visual inspection systems. The installed security alarms are intended to prevent weapons being brought onto aircraft; yet they are often set to such high sensitivity that they alarm many times a day for minor items, such as keys, belt buckles, loose change, mobile phones, and tacks in shoes.

The ratio of false positives (identifying an innocent traveller as a terrorist) to true positives (detecting a would-be terrorist) is, therefore, very high; and because almost every alarm is a false positive, the positive predictive value of these screening tests is very low.

The relative cost of false results determines the likelihood that test creators allow these events to occur. As the cost of a false negative in this scenario is extremely high (not detecting a bomb being brought onto a plane could result in hundreds of deaths) whilst the cost of a false positive is relatively low (a reasonably simple further inspection) the most appropriate test is one with a low statistical specificity but high statistical sensitivity (one that allows a high rate of false positives in return for minimal false negatives).

Biometrics

Biometric matching, such as for fingerprint recognition, facial recognition or iris recognition, is susceptible to type I and type II errors. The null hypothesis is that the input does identify someone in the searched list of people, so:

• the probability of type I errors is called the "false reject rate" (FRR) or false non-match rate (FNMR),
• while the probability of type II errors is called the "false accept rate" (FAR) or false match rate (FMR).

If the system is designed to rarely match suspects then the probability of type II errors can be called the "false alarm rate". On the other hand, if the system is used for validation (and acceptance is the norm) then the FAR is a measure of system security, while the FRR measures user inconvenience level.

Medicine

Medical screening

In the practice of medicine, there is a significant difference between the applications of screening and testing.

• Screening involves relatively cheap tests that are given to large populations, none of whom manifest any clinical indication of disease (e.g., Pap smears).
• Testing involves far more expensive, often invasive, procedures that are given only to those who manifest some clinical indication of disease, and are most often applied to confirm a suspected diagnosis.

For example, most states in the USA require newborns to be screened for phenylketonuria and hypothyroidism, among other congenital disorders. Although they display a high rate of false positives, the screening tests are considered valuable because they greatly increase the likelihood of detecting these disorders at a far earlier stage.

The simple blood tests used to screen possible blood donors for HIV and hepatitis have a significant rate of false positives; however, physicians use much more expensive and far more precise tests to determine whether a person is actually infected with either of these viruses.

Perhaps the most widely discussed false positives in medical screening come from the breast cancer screening procedure mammography. The US rate of false positive mammograms is up to 15%, the highest in world. One consequence of the high false positive rate in the US is that, in any 10-year period, half of the American women screened receive a false positive mammogram. False positive mammograms are costly, with over $100 million spent annually in the U.S. on follow-up testing and treatment. They also cause women unneeded anxiety. As a result of the high false positive rate in the US, as many as 90-95% of women who get a positive mammogram do not have the condition. The lowest rate in the world is in the Netherlands, 1%. The lowest rates are generally in Northern Europe where mammography films are read twice and a high threshold for additional testing is set (the high threshold decreases the power of the test).

The ideal population screening test would be cheap, easy to administer, and produce zero false-negatives, if possible. Such tests usually produce more false-positives, which can subsequently be sorted out by more sophisticated (and expensive) testing.

Medical testing

False negatives and false positives are significant issues in medical testing. False negatives may provide a falsely reassuring message to patients and physicians that disease is absent, when it is actually present. This sometimes leads to inappropriate or inadequate treatment of both the patient and their disease. A common example is relying on cardiac stress tests to detect coronary atherosclerosis, even though cardiac stress tests are known to only detect limitations of coronary artery blood flow due to advanced stenosis.

False negatives produce serious and counter-intuitive problems, especially when the condition being searched for is common. If a test with a false negative rate of only 10%, is used to test a population with a true occurrence rate of 70%, many of the negatives detected by the test will be false.

False positives can also produce serious and counter-intuitive problems when the condition being searched for is rare, as in screening. If a test has a false positive rate of one in ten thousand, but only one in a million samples (or people) is a true positive, most of the positives detected by that test will be false. The probability that an observed positive result is a false positive may be calculated using Bayes' theorem.

Paranormal investigation

The notion of a false positive is common in cases of paranormal or ghost phenomena seen in images and such, when there is another plausible explanation. When observing a photograph, recording, or some other evidence that appears to have a paranormal origin, a false positive is a disproven piece of media "evidence" (image, movie, audio recording, etc.) that actually has a natural explanation.

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See also

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Notes

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References

• Betz, M.A. & Gabriel, K.R., "Type IV Errors and Analysis of Simple Effects", Journal of Educational Statistics, Vol.3, No.2, (Summer 1978), pp. 121-144.
• David, F.N., "A Power Function for Tests of Randomness in a Sequence of Alternatives", Biometrika, Vol.34, Nos.3/4, (December 1947), pp. 335-339.
• Fisher, R.A., The Design of Experiments, Oliver & Boyd (Edinburgh), 1935.
• Gambrill, W., "False Positives on Newborns' Disease Tests Worry Parents", Health Day, (5 June 2006). 34471.html
• Kaiser, H.F., "Directional Statistical Decisions", Psychological Review, Vol.67, No.3, (May 1960), pp. 160-167.
• Kimball, A.W., "Errors of the Third Kind in Statistical Consulting", Journal of the American Statistical Association, Vol.52, No.278, (June 1957), pp. 133-142.
• Lubin, A., "The Interpretation of Significant Interaction", Educational and Psychological Measurement, Vol.21, No.4, (Winter 1961), pp. 807-817.
• Marascuilo, L.A. & Levin, J.R., "Appropriate Post Hoc Comparisons for Interaction and nested Hypotheses in Analysis of Variance Designs: The Elimination of Type-IV Errors", American Educational Research Journal, Vol.7., No.3, (May 1970), pp. 397-421.
• Mitroff, I.I. & Featheringham, T.R., "On Systemic Problem Solving and the Error of the Third Kind", Behavioral Science, Vol.19, No.6, (November 1974), pp. 383-393.
• Mosteller, F., "A k-Sample Slippage Test for an Extreme Population", The Annals of Mathematical Statistics, Vol.19, No.1, (March 1948), pp. 58-65.
• Moulton, R.T., "Network Security", Datamation, Vol.29, No.7, (July 1983), pp. 121-127.
• Raiffa, H., Decision Analysis: Introductory Lectures on Choices Under Uncertainty, Addison-Wesley, (Reading), 1968.

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External links

• Bias and Confounding - presentation by Nigel Paneth, Graduate School of Public Health, University of Pittsburgh

Source of the article : Wikipedia